Basal forebrain modulation of olfactory coding in vivo
نویسندگان
چکیده
Sensory perception is one of the most fundamental brain functions allowing individuals to properly interact and adapt a constantly changing environment. This process requires integration bottom-up top-down neuronal activity that centrally mediated by basal forebrain, region has been linked series cognitive processes such as attention alertness.
 Here, we review latest research using optogenetic approaches in rodents vivo electrophysiological recordings are shedding light into role this regulating olfactory processing decision-making. Moreover, summarize evidence highlighting anatomical physiological differences forebrain with autism spectrum disorder, which could underpin sensory abnormalities they exhibit propose line potential opportunity understand neurobiological basis disorder.
منابع مشابه
Cholinergic inputs from Basal forebrain add an excitatory bias to odor coding in the olfactory bulb.
Cholinergic modulation of central circuits is associated with active sensation, attention, and learning, yet the neural circuits and temporal dynamics underlying cholinergic effects on sensory processing remain unclear. Understanding the effects of cholinergic modulation on particular circuits is complicated by the widespread projections of cholinergic neurons to telencephalic structures that t...
متن کاملOrexin/hypocretin modulation of the basal forebrain cholinergic system: insights from in vivo microdialysis studies.
Since its discovery less than a decade ago, interest in the hypothalamic orexin/hypocretin system has blossomed due to the diversity and importance of the roles played by these neuropeptides. Orexin neurons have widespread projections throughout the central nervous system and intense research has focused on elucidating the pathways and mechanisms by which orexins exert their diverse array of fu...
متن کاملBasal forebrain dynamics during nonassociative and associative olfactory learning.
Cholinergic and GABAergic projections from the horizontal diagonal band (HDB) and medial preoptic area (MCPO) of the basal forebrain to the olfactory system are associated with odor discrimination and odor learning, as well as modulation of neural responses in olfactory structures. Whereas pharmacological and lesion studies give insights into the functional role of these modulatory inputs on a ...
متن کاملRedundant basal forebrain modulation in taste aversion memory formation.
Mnemonic deficits resulting from excitotoxic lesion of the basal forebrain have been classically attributed to the resulting depletion of cortical acetylcholine activity. It has been demonstrated that in spite of the strong cholinergic depletion after injections into the basal forebrain of the immunotoxin 192IgG-saporin, no detectable deficit can be found in the acquisition of several learning ...
متن کاملBasal forebrain glutamatergic modulation of cortical acetylcholine release.
The mediation of cortical ACh release by basal forebrain glutamate receptors was studied in awake rats fitted with microdialysis probes in medial prefrontal cortex and ipsilateral basal forebrain. Repeated presentation of a stimulus consisting of exposure to darkness with the opportunity to consume a sweetened cereal resulted in a transient increase in cortical ACh efflux. This stimulated relea...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International journal of psychological research
سال: 2023
ISSN: ['2011-2084', '2011-7922']
DOI: https://doi.org/10.21500/20112084.6486